The Foundation has awarded $100,000 to The Children’s Cancer Therapy Development Institute (cc-TDI) in support of DIPG research. The cc-TDI team of Drs Xiaolei Lian, Noah Berlow and Charles Keller is working to develop an antibody-drug conjugate (ADC) for DIPG.

The Foundation has awarded £350,000 to Great Ormond Street Hospital Children's Charity (GOSH Charity) for researchers at University College London (UCL) and GOSH who hope to develop a new treatment for an aggressive type of brain tumour, diffuse midline glioma (DMG), until recently known as DIPG or Diffuse Intrinsic Pontine Glioma, using a patient’s own immune system to attack the cancer cells.

The Foundation has made a further grant of US$200K to Professor Chris Jones to support his continued research into ACVR1 mutations, which will now begin preclinical study of single or combination agent ACVR1 inhibitors.

The Foundation has awarded US$200,000 to the research team led by Duane A. Mitchell, M.D., Ph.D. from The University of Florida’s Brain Tumour Immunotherapy Program.
 

The Foundation has awarded a grant of $130,000 to the Paediatric Brain Tumour Consortium for a Phase 1 Clinical Trial of Panobinostat in Children with Diffuse Intrinsic Pontine Glioma.

Update from Dr Chris Jones' study "The Role of ACVR1 / ALK2". The Foundation awards Dr Chris Jones a further £90,000.